I'm sorry, but it seems that you have something us doctors or maybe you are painting everyone with the same brush. In any case I'm not here to defend or accuse anyone. My reply was meant for the person who started the thread initially.
However you are right in some way, yes there is a lot of the human mind that we no one understands, however there is a lot that has already been proven and established as facts. The dys-regulation of Serotonin being one of them. Use of other more modern investigations have also backed evidence suggesting which parts of the brain are at play in depression for example. There has been documented of, ventricular enlargement, smaller hippocampal volumes, cortical grey matter volume reduction in subgenual prefrontal cortex, orbital frontal cortex and anterior cingulate cortex, Furthermore, Functional neuroimaging techniques (fMRI etc) have shown a range of perfusion, metabolic and cell surface abnormalities in limbic and prefrontal structures of the brain in patients with mood disorders.
There are plenty of other such changes that i could quote, but i think I've made my point - so to summarize yes the brain is a very complex organ to study, but we have made a lot of progress in the field of identifying certain areas/systems that are at play in a depressed patient. Targeting those areas/systems with medications is the main-stray of treatment, obviously its not that straight forward, medications alone aren't the answer. Change in lifestyle, positive constructive activities, routines, good diet, sleep, and psychological well-being helps also.
